Glutamic Aspartic Transaminase
نویسندگان
چکیده
منابع مشابه
Glutamic Aspartic Transaminase
Aspartate and glutamate react instantaneously with the pyridoxal form of the pig heart glutamic aspartic transaminase (1) to yield the corresponding keto acid, converting the enzymebound pyridoxal phosphate to bound pyridoxamine phosphate (2). Other amino acids such as methionine sulfoxide, methionine sulfone, and alanine react much more slowly with the enzyme, but the reaction itself appears t...
متن کاملGlutamic-aspartic Transaminase. 8. Equilibrium Kinetics with Aspartate.
Pig heart “soluble” glutamic-aspartic transaminase (L-aspartate : 2-oxoglutarate aminotransferase, EC 2.6.1.1) will catalyze the exchange of an amino group between glutamate and ketoglutarate without the participation of any other amino acid or keto acid (1). This “exchange transamination” also occurs between aspartate and oxaloacetate. The rates of these reactions are comparable to the physiol...
متن کاملPig Heart Glutamic Aspartic Transaminase Mechanism of Transamination.
24 Rumberg, B., A. Muller, and H. T. Witt, Nature, 194, 854 (1962). 25 Duysens, L. M. N., and J. Amesz, Biochim. et Biophys. Acta, 64, 261 (1962). 26 Crane, F. L., in CIBA Foundation Symposium on Quinones in Electron Transport (London, 1960), ed. C. E. W. Wolstenholme and C. K. O'Connor (London: J. & A. Churchill, Ltd., 1961), p. 36. 27 Clayton, R. K., Biochem. Biophys. Res. Comm., 9, 49 (1962)...
متن کاملGlutamic-Aspartic Transaminase REACTION OF HOLOENZYME WITH SUBSTRATES AND OF APOENZYJIE WITH VITAMIN Be DERIVATIVES*
The general subject of enzymatic transamination has been extensively reviewed by several workers (Braunstein (I) ; Snell (2) ; Meister (3)). Glutamic-aspartic transaminase (L-aspartate : 2-oxoglutarate aminotransferase, EC 2.6.1.1) from pig heart. has been prepared by Jenkins, Yphantis, and Sizer (4) and shown to contain 2 molecules of pyridoxal phosphate per enzyme molecule of molecular weight...
متن کاملGlutamic-aspartic transaminase of Dolichos lablab: participation by iron as a cofactor.
1. The action of carboxypeptidase on insulin and acetylinsulin has been investigated. The results of previous workers that the removal of C-terminal alanine does not affect the biological activity of the insulin molecule, but that removal of C-terminal asparagine does so, have been confirmed. 2. The action of trypsin on insulin has also been investigated. The peptides resulting have been purifi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64386-8